A 10-day course of SPA therapy is beneficial for people with severe knee osteoarthritis. A 24-week randomised, controlled pilot study

Karagülle M1, Karagülle MZ2, Karagülle O2, Dönmez A2, Turan M3
Clin Rheumatol. 2007 Dec;26(12):2063-2071. doi: 10.1007/s10067-007-0618-x. Epub 2007 Apr 13

https://www.ncbi.nlm.nih.gov/pubmed/17431728